Clinical Trials

Research has been the foundation of the 20-year evolution of Urox and Seipel Group.

Clinical Trials

Research has been the foundation of the 20-year evolution of Urox and Seipel Group.

1999 First formulation launched in Australia
2002 Steels et al, ACJ 2002. Pilot, Crateva and horsetail to improve bladder control .
2004 Formulation changes to improve effectiveness.
2006 Schauss et al, FASEB. RDBPCT, 120 participants, shows Crateva and horsetail combination, UroLogic improves symptoms of urinary frequency, incontinence, urgency and nocturia.
2010 Formulation modified to produce faster effects (within 1 month versus 3) with lower dosage (reduced to 2 capsules daily, previously 4/day)
2011 Seipel et al, unpublished pilot trials. Urox reduces symptoms of overactive bladder and urinary incontinence.

2012 Seipel et al, unpublished trials. Urox with added Lindera aggregata produces faster results and within a shorter timeframe than Crateva and horsetail alone.
2018 Schoendorfer et al, Urox RDBPCT, 150 participants. Urox reduced day frequency, nocturia, urgency and urge and stress incontinence. Results occurred within 2 to 4 weeks.
2020 Schloss et al. RDBPCT assessing the efficacy of Urox for treatment of nocturnal enuresis in children. Study protocol published BMC Pediatrics (2019) 19:421
2021 Schloss et al RDBCT found that a novel herbal formula Urox Junior assisted children for the treatment of nocturnal enuresis. 2022 Schloss et al corrigendum. Published Phytomedicine.
2022 Zapata et al, New Kid on the Block: The Efficacy of Phytomedicine Extracts Urox in Reducing Overactive Bladder Symptoms in Rats. Published Frontiers of Molecular Biosciences.

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Bladder Control Background

Storage lower urinary tract (LUTS) include overactive bladder (OAB) symptoms of increased day frequency…
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Latest Research

This study demonstrated significant efficacy and tolerability of the phytomedicine formula, Urox, in the treatment of UI and symptoms of OAB….
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Patents

This study demonstrated significant efficacy and tolerability of the phytomedicine formula, Urox, in the treatment of UI and symptoms of OAB….
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